We are pleased to announce that a GuNA-related research article co-authored by our researchers has been featured on the cover of Organic & Biomolecular Chemistry, a journal published by the Royal Society of Chemistry.

The article reports an improved guanidine protecting group that enables efficient synthesis of GuNA[t-Bu]-modified antisense oligonucleotides and is expected to contribute to further advances in modified nucleic acid technologies.

Authors
Shrestha AR, Hayashi J, Kajino R, Hatanaka R, Horie N, Yamaguchi T, Obika S, Umemoto T.

Article Title
An improved guanidine protecting group for the efficient synthesis of GuNA[t-Bu]-modified antisense oligonucleotides

Journal
Organic & Biomolecular Chemistry 2026, 24, 6390-6399.

Cover Feature
Front cover | Organic & Biomolecular Chemistry | The Royal Society of Chemistry

Article Page
Organic & Biomolecular Chemistry